Interaction of cholesterol with galactocerebroside and galactocerebroside-phosphatidylcholine bilayer membranes.

@article{Ruocco1984InteractionOC,
  title={Interaction of cholesterol with galactocerebroside and galactocerebroside-phosphatidylcholine bilayer membranes.},
  author={Martin J. Ruocco and G. Graham Shipley},
  journal={Biophysical journal},
  year={1984},
  volume={46 6},
  pages={
          695-707
        }
}
The interaction of the galactocerebroside, N-palmitoylgalactosylsphingosine (NPGS), with cholesterol has been studied by differential scanning calorimetry (DSC) and x-ray diffraction. Thermal and structural studies demonstrate complex behavior characterized by two endothermic transitions: transition I (TI approximately equal to 50-60 degrees C) corresponding to an NPGS-cholesterol bilayer gel----bilayer liquid crystal transition II (TII where TI less than TII less than TNPGS) corresponding to… Expand
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Differential scanning calorimetry and x-ray diffraction have been used to study the interaction of hydrated N-palmitoylgalactosylsphingosine (NPGS) and dipalMIToylphosphatidylcholine (DPPC), finding complete miscibility of NPGS into hydrated DPPC bilayers is observed in both the bilayer gel and liquid-crystal phases. Expand
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