Interaction of charged lipid vesicles with planar bilayer lipid membranes: detection by antibiotic membrane probes.

@article{Cohen1976InteractionOC,
  title={Interaction of charged lipid vesicles with planar bilayer lipid membranes: detection by antibiotic membrane probes.},
  author={Jonathan A. Cohen and Mario M. Moronne},
  journal={Journal of supramolecular structure},
  year={1976},
  volume={5 3},
  pages={409-16}
}
A technique has been developed for monitoring the interaction of charged phospholipid vesicles with planar bilayer lipid membranes (BLM) by use of the antibiotics Valinomycin, Nonactin, and Monazomycin as surface-charge probes. Anionic phosphatidylserine vesicles, when added to one aqueous compartment of a BLM, are shown to impart negative surface charge to zwitterionic phosphatidylcholine and phosphatidylethanolamine bilayers. The surface charge is distributed asymmetrically, mainly on the… CONTINUE READING