Interaction of cationic peptides with bacterial membranes.

@article{Fidai1997InteractionOC,
  title={Interaction of cationic peptides with bacterial membranes.},
  author={S. Fidai and Susan W Farmer and Robert E. Hancock},
  journal={Methods in molecular biology},
  year={1997},
  volume={78},
  pages={187-204}
}
A common feature of cationic peptides is that their site of action is at the membrane due to channel formation, and that they tend to possess strong selectivity towards their target membrane. For example, although moth cecropin and bee melittin are members of the same family of peptides that adopt amphipathic a-helical structures, the cecropins are strongly antibacterial and demonstrate minimal eukaryotic selectivity (i.e., toxicity), whereas melittin is a weak antibacterial compound but a… CONTINUE READING

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References

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Showing 1-10 of 28 references

Insect defensin , an inducible antibacterial peptide , forms voltage - dependent channels in MjcracoccM . s / M ? eM . s

  • S Cociancich, A Ghazi, C Hetru, J A Hoffman, L. J Letelher
  • 1993

Bacterial outer membranes evolving concepts ASM News

  • R E W Hancock
  • 1991

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