Interaction of cannabidiol with other antiseizure medications: A narrative review

@article{Gilmartin2020InteractionOC,
  title={Interaction of cannabidiol with other antiseizure medications: A narrative review},
  author={Christopher G.S. Gilmartin and Zoya Dowd and Alasdair Parker and Pooja Devi Harijan},
  journal={Seizure},
  year={2020},
  volume={86},
  pages={189-196}
}
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12 Citations

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Cannabis-based magistral formulation is highly effective as an adjuvant treatment in drug-resistant focal epilepsy in adult patients: an open-label prospective cohort study.

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Updated International Tuberous Sclerosis Complex Diagnostic Criteria and Surveillance and Management Recommendations.

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A case series of five patients receiving adjunctive treatment with CBD showed increases in brivaracetam (BRV) levels by 95% to 280%.

Effect of Cannabidiol on Drop Seizures in the Lennox–Gastaut Syndrome

Among children and adults with the Lennox–Gastaut syndrome, the addition of cannabidiol at a dose of 10 mg or 20 mg per kilogram per day to a conventional antiepileptic regimen resulted in greater reductions in the frequency of drop seizures than placebo.

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The present study aimed to address the nature of the interaction between CBD and clobazam to address speculation that the anticonvulsant efficacy of CBD may simply reflect CBD augmenting clobzam exposure.

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