Interaction of calcium and cholesterol sulphate induces membrane destabilization and fusion: implications for the acrosome reaction.

@article{Cheetham1990InteractionOC,
  title={Interaction of calcium and cholesterol sulphate induces membrane destabilization and fusion: implications for the acrosome reaction.},
  author={James J. Cheetham and Rongjia Chen and Richard M Epand},
  journal={Biochimica et biophysica acta},
  year={1990},
  volume={1024 2},
  pages={
          367-72
        }
}
Cholesterol sulphate is a potent stabilizer of membrane bilayer structure in both dielaidoylphosphatidylethanolamine and egg phosphatidylethanolamine model membranes, however, the addition of calcium abolishes this bilayer stabilization. Calcium also induces fusion and leakage of egg phosphatidylethanolamine large unilamellar vesicles containing cholesterol sulphate, but has no effect on fusion or leakage of egg phosphatidylcholine large unilamellar vesicles containing cholesterol sulphate… CONTINUE READING

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