Interaction of alphaPIX (ARHGEF6) with beta-parvin (PARVB) suggests an involvement of alphaPIX in integrin-mediated signaling.

Abstract

Members of the Rho GTPase family are key regulatory molecules that link surface receptors to the organization of the actin cytoskeleton. It is now well established that these small GTPases are also crucial for neuronal morphogenesis and connectivity. Moreover, mutations in ARHGEF6 (also known as alphaPIX or Cool-2 ), encoding a Rac1/Cdc42-specific guanine… (More)

Topics

Cite this paper

@article{Rosenberger2003InteractionOA, title={Interaction of alphaPIX (ARHGEF6) with beta-parvin (PARVB) suggests an involvement of alphaPIX in integrin-mediated signaling.}, author={Georg Rosenberger and Inka Jantke and Andreas Gal and Kerstin Kutsche}, journal={Human molecular genetics}, year={2003}, volume={12 2}, pages={155-67} }