Interaction of a glucocorticoid-responsive element with regulatory sequences in the promoter region of the mouse tyrosine hydroxylase gene.

@article{Hagerty2001InteractionOA,
  title={Interaction of a glucocorticoid-responsive element with regulatory sequences in the promoter region of the mouse tyrosine hydroxylase gene.},
  author={Tracy Hagerty and Emilio Fern{\'a}ndez and Kevin Lynch and Sophie S-W Wang and William W. Morgan and Randy Strong},
  journal={Journal of neurochemistry},
  year={2001},
  volume={78 6},
  pages={1379-88}
}
The purpose of the work reported here was to determine whether the tyrosine hydroxylase glucocorticoid-responsive element (TH-GRE) interacts with the cyclic AMP pathway and the CRE in regulating mouse TH promoter activity, and whether an additional, previously identified downstream GRE-like element also participates in the function of the TH-GRE and CRE. To determine the role of the cAMP pathway on TH-GRE function, we compared the effects of forskolin and dexamethasone on TH mRNA, TH gene… CONTINUE READING
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