Interaction of V-type ATPase inhibitors and extracellular NAADP-triggered calcium release in skeletal muscle cells

@inproceedings{Hiess2011InteractionOV,
  title={Interaction of V-type ATPase inhibitors and extracellular NAADP-triggered calcium release in skeletal muscle cells},
  author={Florian Hiess and Martin Hohenegger},
  year={2011}
}
Background Nicotinic acid adenine dinucleotide phosphate (NAADP) has been identified as a calcium-mobilizing second messenger. NAADP is regularly enzymatically synthesized by ADP-ribosyl cyclases, in particular under acidic conditions. In nanomolar concentrations NAADP targets selectively the ryanodine receptor type 1 on the sarcoplasmic reticulum, and the… CONTINUE READING