Interaction of Nitric Oxide with Human Heme Oxygenase-1*

@article{Wang2003InteractionON,
  title={Interaction of Nitric Oxide with Human Heme Oxygenase-1*},
  author={Jinling Wang and Shen Lu and P. Mo{\"e}nne-Loccoz and P. Ortiz de Montellano},
  journal={The Journal of Biological Chemistry},
  year={2003},
  volume={278},
  pages={2341 - 2347}
}
NO and CO may complement each other as signaling molecules in some physiological situations. We have examined the binding of NO to human heme oxygenase-1 (hHO-1), an enzyme that oxidizes heme to biliverdin, CO, and free iron, to determine whether inhibition of hHO-1 by NO can contribute to the signaling interplay of NO and CO. An Fe3+-NO hHO-1-heme complex is formed with NO or the NO donors NOC9 or 2-(N,N-diethylamino)-diazenolate-2-oxide·sodium salt. Resonance Raman spectroscopy shows that… Expand
The Interaction of Nitric Oxide with Distinct Hemoglobins Differentially Amplifies Endothelial Heme Uptake and Heme Oxygenase-1 Expression
Post-translational Regulation of Human Indoleamine 2,3-Dioxygenase Activity by Nitric Oxide*
Hemoglobin: A Nitric-Oxide Dioxygenase
Ozonation of Human Blood Induces a Remarkable Upregulation of Heme Oxygenase-1 and Heat Stress Protein-70
A key role for heme oxygenase-1 in nitric oxide resistance in murine motor neurons and glia.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 62 REFERENCES
Proton Delivery in NO Reduction by Fungal Nitric-oxide Reductase
Nitric oxide induces heme oxygenase-1 gene expression in mesangial cells.
Nitric oxide and iron proteins.
  • C. Cooper
  • Chemistry, Medicine
  • Biochimica et biophysica acta
  • 1999
Nitric oxide induces heme oxygenase-1 via mitogen-activated protein kinases ERK and p38.
...
1
2
3
4
5
...