Interaction of HLA and immunoglobulin antigens in Type 1 (insulin-dependent) diabetes

@article{Field1984InteractionOH,
  title={Interaction of HLA and immunoglobulin antigens in Type 1 (insulin-dependent) diabetes},
  author={Leigh L. Field and Claus Erik Andersen and Katherine Neiswanger and Susan E. Hodge and M. Anne Spence and Jerome I. Rotter},
  journal={Diabetologia},
  year={1984},
  volume={27},
  pages={504-508}
}
We analyzed 88 unrelated subjects with Type 1 (insulin-dependent) diabetes and 64 sibling controls (maximum one per diabetic) for associations between immunoglobulin allotype antigens (GM and KM) and Type 1 diabetes. None were found. However, we did find interactions between GM, HLA-DR, and Type 1 diabetes (significant or of borderline significance after… CONTINUE READING