Interaction of DNA with cytosolic 3-methylcholanthrene binding proteins from either rat or mouse liver.

@article{Weaver1980InteractionOD,
  title={Interaction of DNA with cytosolic 3-methylcholanthrene binding proteins from either rat or mouse liver.},
  author={David E. Weaver and Amanda Amos and Brian Tierney and E. Bresnick},
  journal={Carcinogenesis},
  year={1980},
  volume={1 6},
  pages={481-6}
}
The ability of cytosolic 3-methylcholanthrene binding proteins from rat liver to interact with DNA was studied using DNA-cellulose chromatography. Two DNA binding fractions, eluting in 0.15 M KCl (peak 1) and 0.33 M KCl (peak 2), were observed on salt elution from a denatured DNA-cellulose column which had been incubated with rat liver cytosol containing radiolabelled 3-methylcholanthrene. No detectable DNA binding fractions were found when columns containing cellulose alone or native DNA… CONTINUE READING