Interaction of CPCCOEt with a chimeric mGlu1b and calcium sensing receptor.

@article{BrunerOsborne1999InteractionOC,
  title={Interaction of CPCCOEt with a chimeric mGlu1b and calcium sensing receptor.},
  author={Hans Br{\"a}uner-Osborne and Anders A Jensen and Povl Krogsgaard-Larsen},
  journal={Neuroreport},
  year={1999},
  volume={10 18},
  pages={3923-5}
}
7-Hydroxyiminocyclopropan[b]chromen-1a-carboxylic acid ethyl ester (CPCCOEt) has previously been shown to be a selective non-competitive antagonist at the metabotropic glutamate (mGlu) receptor subtype 1. In this study we have tested the effect of CPCCOEt on mGlu1b, the calcium sensing receptor (CaR) and a chimeric receptor consisting of the agonist binding amino-terminal domain (ATD) of CaR and the seven transmembrane (7TM) domain of mGlu1b (named Ca/1b). CPCCOEt inhibited responses of (S… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Similar Papers

Loading similar papers…