Interaction of Bordetella pertussis with mast cells, modulation of cytokine secretion by pertussis toxin.

@article{Mielcarek2001InteractionOB,
  title={Interaction of Bordetella pertussis with mast cells, modulation of cytokine secretion by pertussis toxin.},
  author={Nathalie Mielcarek and Elisabeth Hultgren H{\"o}rnquist and Bengt R. Johansson and Camille Locht and Soman N. Abraham and Jan Holmgren},
  journal={Cellular microbiology},
  year={2001},
  volume={3 3},
  pages={
          181-8
        }
}
Together with macrophages and dendritic cells, mast cells have recently been shown to interact with certain pathogenic bacteria and present microbial antigens to the immune system. We show here that Bordetella pertussis can adhere to and be phagocytosed by mast cells. In addition, mast cells are able to process and present B. pertussis antigens to T lymphocytes. Furthermore, exposure of mast cells to B. pertussis induced the release of the proinflammatory cytokines tumour necrosis factor alpha… CONTINUE READING

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