Interaction of Bartonella henselae with endothelial cells results in bacterial aggregation on the cell surface and the subsequent engulfment and internalisation of the bacterial aggregate by a unique structure, the invasome.

@article{Dehio1997InteractionOB,
  title={Interaction of Bartonella henselae with endothelial cells results in bacterial aggregation on the cell surface and the subsequent engulfment and internalisation of the bacterial aggregate by a unique structure, the invasome.},
  author={Christoph Dehio and Manfred Meyer and Jeffrey S Berger and Heinz J. Schwarz and C Lanz},
  journal={Journal of cell science},
  year={1997},
  volume={110 ( Pt 18)},
  pages={
          2141-54
        }
}
Vascular colonisation by Bartonella henselae may cause vaso-proliferative tumour growth with clumps of bacteria found in close association with proliferating endothelial cells. By using B. henselae-infected human umbilical vein endothelial cells as an in vitro model for endothelial colonisation, we report here on a novel mechanism of cellular invasion by bacteria. First, the leading lamella of endothelial cells establishes cellular contact to sedimented bacteria and mediates bacterial… CONTINUE READING
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