Interaction of Bacillus subtilis CsaA with SecA and precursor proteins.

  title={Interaction of Bacillus subtilis CsaA with SecA and precursor proteins.},
  author={Jens Peter M{\"u}ller and J{\"o}rg H Ozegowski and S. Vettermann and Jelto Swaving and K H van Wely and Arnold J M Driessen},
  journal={The Biochemical journal},
  volume={348 Pt 2},
CsaA from the Gram-positive bacterium Bacillus subtilis has been identified previously as a suppressor of the growth and protein-export defect of Escherichia coli secA(Ts) mutants. CsaA has chaperone-like activities in vivo and in vitro. To examine the role of CsaA in protein export in B. subtilis, expression of the csaA gene was repressed. While export of most proteins remained unaffected, export of at least two proteins was significantly reduced upon CsaA depletion. CsaA co-immunoprecipitates… CONTINUE READING
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