Interaction of Afobazole with σ1-Receptors

@article{Seredenin2009InteractionOA,
  title={Interaction of Afobazole with $\sigma$1-Receptors},
  author={Sergey B. Seredenin and Tatiana A. Antipova and Mikhail V. Voronin and Svetlana Yu Kurchashova and Alexander N. Kuimov},
  journal={Bulletin of Experimental Biology and Medicine},
  year={2009},
  volume={148},
  pages={42-44}
}
In vitro radioligand assay revealed interaction of afobazole with σ1-receptors (Ki=5.9 × 10—6 M). Translocation of σ1-receptors from the endoplasmic reticulum to the outer membrane was demonstrated by confocal microscopy. Experiments were performed on the model of HT-22 immortalized hippocampal cells after incubation with afobazole in a concentration of 10—8 M. 
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