Interaction of [3H]dipyridamole with the nucleoside transporters of human erythrocytes and cultured animal cells


Equilibrium binding of [3H]dipyridamole identified high-affinity (K i ∼10nm) binding sites on human erythrocytes (∼5×105 sites/cell) and on HeLa cells (∼5×106 sites/cell). The equilibration of dipyridamole with these sites on human erythrocytes was compatible with a second-order process which proceeded at 22°C with a rate constant of about 6×106 m −1 sec−1… (More)
DOI: 10.1007/BF01871048


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