Interaction graph mining for protein complexes using local clique merging.

  title={Interaction graph mining for protein complexes using local clique merging.},
  author={Xiaoli Li and Soon-Heng Tan and Chuan-Sheng Foo and See-Kiong Ng},
  journal={Genome informatics. International Conference on Genome Informatics},
  volume={16 2},
While recent technological advances have made available large datasets of experimentally-detected pairwise protein-protein interactions, there is still a lack of experimentally-determined protein complex data. To make up for this lack of protein complex data, we explore the mining of existing protein interaction graphs for protein complexes. This paper proposes a novel graph mining algorithm to detect the dense neighborhoods (highly connected regions) in an interaction graph which may… CONTINUE READING

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