Interaction between tobacco smoke and alcohol in animal models.

@article{Florek2008InteractionBT,
  title={Interaction between tobacco smoke and alcohol in animal models.},
  author={Ewa Florek and Wojciech Piekoszewski and Maksymilian Kulza and Tamar Szindzikaszwili and Ewa Gom{\'o}łka and Marek Chuchracki and Anna Sedziak},
  journal={Pharmacological reports : PR},
  year={2008},
  volume={60 6},
  pages={985-90}
}
This study aimed to evaluate the impact of nicotine and other xenobiotics contained in tobacco smoke on the pharmacokinetics of ethyl alcohol and on the levels of toxic ethanol metabolites such as acetic aldehyde.We also sought to evaluate the impact of a one-time administration of ethyl alcohol on the biotransformation of nicotine, the addictive alkaloid of tobacco smoke, to its main metabolite, cotinine. Rats were divided in three groups. The first group was exposed to tobacco smoke (6 h per… CONTINUE READING

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