Interaction between the motor protein prestin and the transporter protein VAPA.

  title={Interaction between the motor protein prestin and the transporter protein VAPA.},
  author={Soma Sengupta and Katharine K. Miller and Kazuaki Homma and Roxanne M. Edge and Mary Ann Cheatham and Peter Dallos and Jing Zheng},
  journal={Biochimica et biophysica acta},
  volume={1803 7},
Prestin is the motor protein responsible for cochlear outer hair cell (OHC) somatic electromotility. Eliminating this abundant basolateral membrane protein not only causes loss of frequency selectivity and hearing sensitivity, but also leads to OHC death. A membrane-based yeast two-hybrid approach was used to screen an OHC-enriched cDNA (complementary Deoxyribonucleic Acid) library in order to identify prestin-associated proteins. Several proteins were recognized as potential prestin partners… CONTINUE READING
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Evaluation of an independent prestin mouse model derived from the 129S1 strain, Audiol. Neurootol

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  • 2007
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