Interaction between several medicines and statins.

  title={Interaction between several medicines and statins.},
  author={Hideki Fujino and Tsuyoshi Saito and Yoshihiko Tsunenari and Junji Kojima},
  volume={53 3},
To gain a better understanding of drug-drug interaction between various medicinal substances and statins, in vitro experiments using human hepatic microsomes were performed. The metabolic clearance of atorvastatin (CAS 134523-00-5) was about 32 microliters/min/mg protein, some 15-fold greater than that of pitavastatin (CAS 147526-32-7). On co-incubation… CONTINUE READING