Interaction between poor glycemic control and 9p21 locus on risk of coronary artery disease in type 2 diabetes.

@article{Doria2008InteractionBP,
  title={Interaction between poor glycemic control and 9p21 locus on risk of coronary artery disease in type 2 diabetes.},
  author={Alessandro Doria and Joanna Wojcik and Rui Xu and Ernest V. Gervino and Thomas H. Hauser and Michael T. Johnstone and David N Nolan and Frank B Hu and James H. Warram},
  journal={JAMA},
  year={2008},
  volume={300 20},
  pages={2389-97}
}
CONTEXT A common allele on chromosome 9p21 has been repeatedly associated with increased risk of coronary artery disease (CAD) in the general population. However, the magnitude of this effect in the population with diabetes has not been well characterized. OBJECTIVE To examine the association of the 9p21 variant with CAD in individuals with type 2 diabetes and evaluate its interaction with poor glycemic control. DESIGN, SETTING, AND PARTICIPANTS (1) Case-control study of 734 type 2 diabetes… CONTINUE READING
55 Citations
43 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 55 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 43 references

ceptibility to coronary artery disease and diabetes is encoded by distinct , tightly linked SNPs in the ANRIL locus on chromosome 9 p

  • A Kamb, NA Gruis, J Weaver-Feldhaus
  • Hum Mol Genet
  • 2008

A common allele on chromosome 8 associated with coronary artery disease

  • R McPherson, A Pertsemlidis, N Kavaslar
  • Science
  • 2007
2 Excerpts

Ge - nomewide association study of 14 000 cases of seven common diseases and 3000 shared controls

  • NJ Samani, J Erdmann, AS Hall
  • Nature
  • 2007

Similar Papers

Loading similar papers…