Interaction between polypeptide 3ABC and the 5'-terminal structural elements of the genome of Aichi virus: implication for negative-strand RNA synthesis.

@article{Nagashima2008InteractionBP,
  title={Interaction between polypeptide 3ABC and the 5'-terminal structural elements of the genome of Aichi virus: implication for negative-strand RNA synthesis.},
  author={Shigeo Nagashima and Jun Sasaki and Koki Taniguchi},
  journal={Journal of virology},
  year={2008},
  volume={82 13},
  pages={6161-71}
}
Secondary structural elements at the 5' end of picornavirus genomic RNA function as cis-acting replication elements and are known to interact specifically with viral P3 proteins in several picornaviruses. In poliovirus, ribonucleoprotein complex formation at the 5' end of the genome is required for negative-strand synthesis. We have previously shown that… CONTINUE READING