Interaction between overweight and genotypes of HLA, TCF7L2, and FTO in relation to the risk of Latent Autoimmune Diabetes in Adults and type 2 diabetes.

  title={Interaction between overweight and genotypes of HLA, TCF7L2, and FTO in relation to the risk of Latent Autoimmune Diabetes in Adults and type 2 diabetes.},
  author={Rebecka Hjort and Josefin E. L{\"o}fvenborg and Emma Ahlqvist and Lars Alfredsson and Tomas Andersson and Valdemar E Grill and Leif C. Groop and Elin P. S{\o}rgjerd and Tiinamaija Tuomi and Bj{\o}rn Olav {\AA}svold and Sofia Carlsson},
  journal={The Journal of clinical endocrinology and metabolism},
OBJECTIVES We investigated potential interactions between BMI and genotypes of human leukocyte antigen (HLA), TCF7L2-rs7903146 and FTO-rs9939609 in relation to the risk of latent autoimmune diabetes in adults (LADA) and type 2 diabetes. METHODS We pooled data from two population-based studies; a Swedish study with incident cases of LADA (GADA positive, n=394) and type 2 diabetes (GADA negative, n=1,290) and matched non-diabetic controls (n=2,656) and a prospective Norwegian study, including… 

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