Interaction between organochlorines and the AHR gene, and risk of non-Hodgkin lymphoma

@article{Ng2009InteractionBO,
  title={Interaction between organochlorines and the AHR gene, and risk of non-Hodgkin lymphoma},
  author={Carmen H. Ng and Rozmin T Janoo-Gilani and Payal Sipahimalani and Richard P. Gallagher and Randy D. Gascoyne and Joseph M. Connors and J Weber and Agnes S. Lai and Stephen R. Leach and Nhu D. Le and Angela Brooks-Wilson and John Spinelli},
  journal={Cancer Causes & Control},
  year={2009},
  volume={21},
  pages={11-22}
}
Plasma organochlorines have been implicated to increase the risk of non-Hodgkin lymphoma (NHL), and interaction with the aryl hydrocarbon receptor gene (AHR) may modify this risk. In this case–control study conducted in British Columbia, Canada, five single nucleotide polymorphisms (SNPs) of AHR were genotyped in 422 NHL cases and 459 controls to measure the association between individual SNPs, haplotypes, and risk of NHL. Pre-chemotherapy organochlorine levels were measured and gene… CONTINUE READING