Interaction between neurokinin A, VIP, prostanoids, and enteric nerves in regulation of duodenal function.

@article{Hllgren1998InteractionBN,
  title={Interaction between neurokinin A, VIP, prostanoids, and enteric nerves in regulation of duodenal function.},
  author={Anneli H{\"a}llgren and Gunnar Flemstr{\"o}m and Olof Nylander},
  journal={The American journal of physiology},
  year={1998},
  volume={275 1 Pt 1},
  pages={
          G95-103
        }
}
Neurokinin A (NKA) induces duodenal motility and increases mucosal permeability and bicarbonate secretion in the in situ perfused duodenum in anesthetized rats. In the present study, the NKA-induced increase in mucosal permeability was potentiated by luminal perfusion with lidocaine and diminished by vasoactive intestinal peptide (VIP) but unaltered by elevated intraluminal pressure. Elevation of intraluminal pressure, however, potentiated the stimulatory effect of NKA on bicarbonate secretion… CONTINUE READING

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