Interaction between exercise and food restriction: effects on longevity of male rats.

@article{Holloszy1991InteractionBE,
  title={Interaction between exercise and food restriction: effects on longevity of male rats.},
  author={John O. Holloszy and Kenneth B. Schechtman},
  journal={Journal of applied physiology},
  year={1991},
  volume={70 4},
  pages={1529-35}
}
Male rats that exercise in running wheels have a longer average survival than freely eating sedentary controls but, in contrast to food-restricted sedentary controls of the same weight, show no extension of maximal life span (J. Appl. Physiol. 59: 826-831, 1985). To test the possibility that exercise may counteract a life-extending effect of decreased availability of energy for certain biological processes such as cell proliferation, we examined the combined effects of exercise and food… CONTINUE READING