Interaction between estrogens and antidepressants in the forced swimming test in rats

@article{EstradaCamarena2003InteractionBE,
  title={Interaction between estrogens and antidepressants in the forced swimming test in rats},
  author={Erika Estrada-Camarena and Alonso Fern{\'a}ndez-Guasti and Carolina L{\'o}pez-Rubalcava},
  journal={Psychopharmacology},
  year={2003},
  volume={173},
  pages={139-145}
}
Several reports suggest that estrogens possess antidepressant effects and could facilitate the action of some antidepressants. To analyze the interaction between three different types of estrogens, 17β-estradiol (E2), ethinylestradiol (EE2) or diethyl-stilbestrol (DES) and the antidepressants, fluoxetine (FLX) or desipramine (DMI) in ovariectomized female rats subjected to an animal model for the study of antidepressant compounds, the forced swimming test (FST). The effect of the combination of… CONTINUE READING