Interaction between effects of genes coding for dopamine and glutamate transmission on striatal and parahippocampal function.

@article{Pauli2013InteractionBE,
  title={Interaction between effects of genes coding for dopamine and glutamate transmission on striatal and parahippocampal function.},
  author={Andreina Pauli and Diana P. Prata and Andrea Mechelli and Marco M. Picchioni and Cynthia H. Y. Fu and Christopher A. Chaddock and Fergus Kane and Sridevi Kalidindi and Colm McDonald and Eugenia Kravariti and Timothea Toulopoulou and Elvira Bramon and Muriel Walshe and Natascha Ehlert and Anna Georgiades and Robin M. Murray and David A. Collier and Philip K. McGuire},
  journal={Human brain mapping},
  year={2013},
  volume={34 9},
  pages={
          2244-58
        }
}
The genes for the dopamine transporter (DAT) and the D-Amino acid oxidase activator (DAOA or G72) have been independently implicated in the risk for schizophrenia and in bipolar disorder and/or their related intermediate phenotypes. DAT and G72 respectively modulate central dopamine and glutamate transmission, the two systems most robustly implicated in these disorders. Contemporary studies have demonstrated that elevated dopamine function is associated with glutamatergic dysfunction in… CONTINUE READING
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Interactive effects of DAOA ( G 72 ) and catechol - O - methyltransferase on neurophysiology in prefrontal cortex

  • DC Nixon, MJ Prust, F Sambataro, HY Tan, VS Mattay, JH Callicott
  • Biol Psychiatry
  • 2011
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