Interaction between cyclooxygenase-2 gene polymorphism and dietary n-6 polyunsaturated fatty acids on colon cancer risk: The Singapore Chinese Health Study

@article{Koh2004InteractionBC,
  title={Interaction between cyclooxygenase-2 gene polymorphism and dietary n-6 polyunsaturated fatty acids on colon cancer risk: The Singapore Chinese Health Study},
  author={W M Koh and Jian-Min Yuan and David J. Van Den Berg and H-P Lee and Mimi C. Yu},
  journal={British Journal of Cancer},
  year={2004},
  volume={90},
  pages={1760 - 1764}
}
This case–control study of 310 colorectal cancer cases and 1177 controls in a nested prospective, population-based cohort of Singapore Chinese subjects found a statistically significant association between the cyclooxygenase (COX)-2 −765G>C gene polymorphism and colon cancer risk among high consumers of dietary n-6 polyunsaturated fatty acids (odds ratio=2.38, 95% confidence interval=1.23–4.59). 

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This case – control study of 310 colorectal cancer cases and 1177 controls in a nested prospective , population - based cohort of Singapore Chinese subjects found a statistically significant association between the cyclooxygenase ( COX)-2 −765G > C gene polymorphism and colon cancer risk among high consumers of dietary n-6 polyunsaturated fatty acids ( odds ratio=2.38 , 95% confidence interval=1.23–4.59 ) .
This case – control study of 310 colorectal cancer cases and 1177 controls in a nested prospective , population - based cohort of Singapore Chinese subjects found a statistically significant association between the cyclooxygenase ( COX)-2 −765G > C gene polymorphism and colon cancer risk among high consumers of dietary n-6 polyunsaturated fatty acids ( odds ratio=2.38 , 95% confidence interval=1.23–4.59 ) .
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