Interaction between corticosteroid binding globulin and activated leukocytes in vitro.

@article{Hammond1990InteractionBC,
  title={Interaction between corticosteroid binding globulin and activated leukocytes in vitro.},
  author={Geoffrey L. Hammond and Carolyn L. Smith and C M Underhill and Van Trung Nguyen},
  journal={Biochemical and biophysical research communications},
  year={1990},
  volume={172 1},
  pages={172-7}
}
The interaction between human corticosteroid binding globulin and activated leukocytes is restricted to the granulocyte population, and is characterized by specific proteolytic cleavage of corticosteroid binding globulin which markedly reduces its steroid binding activity. A direct interaction between corticosteroid binding globulin and the activated cells appears to enhance this event, and does not involve cellular internalization of corticosteroid binding globulin or its proteolytic… CONTINUE READING