Interaction between chlorhexidine digluconate and sodium lauryl sulfate in vivo.

@article{Barkvoll1989InteractionBC,
  title={Interaction between chlorhexidine digluconate and sodium lauryl sulfate in vivo.},
  author={P{\aa}l Barkvoll and Gunnar R\olla and Ken Svendsen},
  journal={Journal of clinical periodontology},
  year={1989},
  volume={16 9},
  pages={593-5}
}
Chlorhexidine (CH) is cationic and it forms salts of low solubility with anions such as phosphate, sulfate and carboxyl. Toothpastes contain anionic detergents, one of the most widely used being sodium lauryl sulfate (SLS). The aim of the present study was to examine the possible interaction between CH and the anion SLS in vivo. The interference of SLS on the antiplaque potential of CH was investigated. The study was performed according to a single blind cross over design, and the effect of the… CONTINUE READING
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