Interaction between antidepressants and alcohol: signal amplification by multiple case reports.

  title={Interaction between antidepressants and alcohol: signal amplification by multiple case reports.},
  author={David Benjamin Menkes and Andrew Herxheimer},
  journal={The International journal of risk \& safety in medicine},
  volume={26 3},
  • D. MenkesA. Herxheimer
  • Published 2014
  • Medicine, Psychology
  • The International journal of risk & safety in medicine
BACKGROUND Alcohol use and antidepressant prescription are prevalent in many countries, but little is known about their combined effects. OBJECTIVE Having been surprised by selective serotonin reuptake inhibitor (SSRI) antidepressant-treated patients who became prone to pathological intoxication, we examined this association, searching for relevant literature and cases. METHODS A detailed literature search showed little or no interaction between SSRIs and alcohol in laboratory studies, and… 

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