Interaction between anaesthetics and model biomembrane systems

  title={Interaction between anaesthetics and model biomembrane systems},
  author={Jos{\'e} Gabriel Paiva and Benilde Saramago and Ana Paula Serro},
  journal={1st Portuguese Biomedical Engineering Meeting},
Supported layers of vesicles of dimyristoyl and dipalmitoyl phosphatidylcholine containing cholesterol are adequate models for eukaryotic plasma membranes. In this work it was investigated the adsorption of unilamellar vesicles on the surface of oxidized gold, using a QCM-D, AFM and LSCFM. The results of all techniques indicate that a dense layer of intact liposomes irreversibly adsorbs on the gold surface. It was also investigated the interaction of some examples of local and general… CONTINUE READING