Interaction between adrenaline and epidermal growth factor in the control of liver glycogenolysis in mouse.

  title={Interaction between adrenaline and epidermal growth factor in the control of liver glycogenolysis in mouse.},
  author={Montserrat Bosch Grau and Maria Soley and Ignasi Ram{\'i}rez},
  volume={138 6},
Epidermal growth factor (EGF) stimulates glycogenolysis in mouse liver, but the effect requires concentrations that are only achieved in plasma upon adrenergic stimulation of EGF release from submandibular salivary glands. Thus, we studied the interaction between adrenaline and EGF in liver glycogen metabolism, both in whole animals and in isolated hepatocytes. Adrenaline administered to anesthetized mice stimulated both the endocrine secretion of EGF from submandibular salivary glands and the… CONTINUE READING


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