Interaction between a functional MAOA locus and childhood sexual abuse predicts alcoholism and antisocial personality disorder in adult women

@article{Ducci2008InteractionBA,
  title={Interaction between a functional MAOA locus and childhood sexual abuse predicts alcoholism and antisocial personality disorder in adult women},
  author={Francesca Ducci and M A Enoch and Colin Hodgkinson and Ke Xu and Mario Catena Catena and Robert W. Robin and David Goldman},
  journal={Molecular Psychiatry},
  year={2008},
  volume={13},
  pages={334-347}
}
Women who have experienced childhood sexual abuse (CSA) have an increased risk of alcoholism and antisocial personality disorder (ASPD). Among male subjects, a functional polymorphism (MAOA-LPR, monoamine oxidase A linked polymorphic region) in the promoter region of the monoamine oxidase A gene (MAOA) appears to moderate the effect of childhood maltreatment on antisocial behavior. Our aim was to test whether MAOA-LPR influences the impact of CSA on alcoholism and ASPD in a sample of 291 women… CONTINUE READING
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