Interaction between S100P and the anti-allergy drug cromolyn.

@article{Penumutchu2014InteractionBS,
  title={Interaction between S100P and the anti-allergy drug cromolyn.},
  author={Srinivasa R. Penumutchu and Ruey Hwang Chou and Chin Yu},
  journal={Biochemical and biophysical research communications},
  year={2014},
  volume={454 3},
  pages={404-9}
}
The S100P protein has been known to mediate cell proliferation by binding the receptor for advanced glycation end products (RAGE) to activate signaling pathways, such as the extracellular regulated kinase (ERK) and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) pathways. S100P/RAGE signaling is involved in a variety of diseases, such as cancer, metastasis, and diabetes. Cromolyn is an anti-allergy drug that binds S100P to block the interaction between S100P and RAGE. In… CONTINUE READING
1 Citations
36 References
Similar Papers

Citations

Publications citing this paper.

References

Publications referenced by this paper.
Showing 1-10 of 36 references

The crystal structure at 2 angstrom resolution of the Ca 2 + - binding protein S 100 P

  • G. Z. Wang, Y. Ding, +4 authors Z. H. Rao
  • J . Grid Comput .
  • 2012

Logsdon, S100P: a novel therapeutic target for cancer

  • C.D.T. Arumugam
  • Amino Acids
  • 2011
1 Excerpt

S 100 P : a novel therapeutic target for cancer

  • M. K. Fuentes, T. Arumugam, C. D. Logsdon
  • Amino Acids
  • 2011

Similar Papers

Loading similar papers…