Interaction between N-acetylcysteine and activated charcoal: implications for the treatment of acetaminophen poisoning.

@article{Tenenbein2001InteractionBN,
  title={Interaction between N-acetylcysteine and activated charcoal: implications for the treatment of acetaminophen poisoning.},
  author={Paul K. Tenenbein and Daniel S. Sitar and Milton Tenenbein},
  journal={Pharmacotherapy},
  year={2001},
  volume={21 11},
  pages={
          1331-6
        }
}
  • Paul K. Tenenbein, Daniel S. Sitar, Milton Tenenbein
  • Published 2001
  • Chemistry, Medicine
  • Pharmacotherapy
  • STUDY OBJECTIVE To determine if the presence of N-acetylcysteine reduces the ability of activated charcoal to adsorb acetaminophen both in the absence and presence of a coingestant. DESIGN In vitro laboratory study. SETTING University hospital research laboratory. MEASUREMENTS AND MAIN RESULTS The adsorption of acetaminophen and salicylic acid by activated charcoal in the presence and absence of N-acetylcysteine was measured in vitro. Acetaminophen and salicylic acid analyses were… CONTINUE READING

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