Interaction between Epsin/Yap180 adaptors and the scaffolds Ede1/Pan1 is required for endocytosis.

@article{MaldonadoBez2008InteractionBE,
  title={Interaction between Epsin/Yap180 adaptors and the scaffolds Ede1/Pan1 is required for endocytosis.},
  author={Lymarie Maldonado-B{\'a}ez and Michael Robert Dores and Edward M. Perkins and Theodore G. Drivas and Linda Hicke and Beverly Wendland},
  journal={Molecular biology of the cell},
  year={2008},
  volume={19 7},
  pages={
          2936-48
        }
}
The spatial and temporal regulation of the interactions among the approximately 60 proteins required for endocytosis is under active investigation in many laboratories. We have identified the interaction between monomeric clathrin adaptors and endocytic scaffold proteins as a critical prerequisite for the recruitment and/or spatiotemporal dynamics of endocytic proteins at early and late stages of internalization. Quadruple deletion yeast cells (DeltaDeltaDeltaDelta) lacking four putative… CONTINUE READING

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