Interaction between Borrelia burgdorferi and immature human dendritic cells.

  title={Interaction between Borrelia burgdorferi and immature human dendritic cells.},
  author={Jukka Suhonen and Janne O Komi and Jori Soukka and Olli Lassila and Matti K. Viljanen},
  journal={Scandinavian journal of immunology},
  volume={58 1},
Antigen uptake and the following maturation of dendritic cells (DCs) are pivotal to the initiation of specific antimicrobial immune responses. DCs also play an important role in the recruitment and activation of the cells of the innate immune system. We have examined the interactions of DCs with Borrelia burgdorferi to find explanations for the difficulties the human immune system has in dealing with the bacterium. Phagocytosis of B. burgdorferi by immature DCs and the effect of the bacterium… CONTINUE READING
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