Interaction between APOA5 -1131T>C and APOE polymorphisms and their association with severe hypertriglyceridemia.

@article{Sousa2008InteractionBA,
  title={Interaction between APOA5 -1131T>C and APOE polymorphisms and their association with severe hypertriglyceridemia.},
  author={Marinez de Oliveira Sousa and Pedro Al{\'i}a and Xavier Pint{\'o} and Emili Corbella and Miguel-Angel Moreno Navarro},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2008},
  volume={395 1-2},
  pages={68-71}
}
BACKGROUND Apolipoprotein A5 gene (APOA5) has been shown to modulate plasma triglyceride concentrations. The apolipoprotein E gene (APOE) has been implicated in cholesterol and triglyceride homeostasis in humans and plays an important role in atherogenesis. The aim of this study was to determine the genotypic distribution of the APOA5 -1131T>C and APOE polymorphisms and to identify the combined association of these variants between patients with and without severe hypertriglyceridemia (HTG… CONTINUE READING
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