Interaction among nitric oxide (NO)-related genes in migraine susceptibility

@article{Gonalves2012InteractionAN,
  title={Interaction among nitric oxide (NO)-related genes in migraine susceptibility},
  author={F. M. Gonçalves and M. Luizon and J. Speciali and A. Martins‐Oliveira and F. Dach and J. Tanus-Santos},
  journal={Molecular and Cellular Biochemistry},
  year={2012},
  volume={370},
  pages={183-189}
}
The pathogenic mechanisms involved in migraine are complex and not completely clarified. Because there is evidence for the involvement of nitric oxide (NO) in migraine pathophysiology, candidate gene approaches focusing on genes affecting the endothelial function have been studied including the genes encoding endothelial NO synthase (eNOS), inducible NO synthase (iNOS), and vascular endothelial growth factor (VEGF). However, investigations on gene–gene interactions are warranted to better… Expand
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