Interaction among autoregulation, CO2 reactivity, and intracranial pressure: a mathematical model.

@article{Ursino1998InteractionAA,
  title={Interaction among autoregulation, CO2 reactivity, and intracranial pressure: a mathematical model.},
  author={Mauro Ursino and Carlo Alberto Lodi},
  journal={The American journal of physiology},
  year={1998},
  volume={274 5 Pt 2},
  pages={H1715-28}
}
The relationships among cerebral blood flow, cerebral blood volume, intracranial pressure (ICP), and the action of cerebrovascular regulatory mechanisms (autoregulation and CO2 reactivity) were investigated by means of a mathematical model. The model incorporates the cerebrospinal fluid (CSF) circulation, the intracranial pressure-volume relationship, and cerebral hemodynamics. The latter is based on the following main assumptions: the middle cerebral arteries behave passively following… CONTINUE READING
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