Interaction Between MMP-9 Gene Polymorphisms and Smoking in Relation to Myocardial Infarction in a Uighur Population

@article{Wang2012InteractionBM,
  title={Interaction Between MMP-9 Gene Polymorphisms and Smoking in Relation to Myocardial Infarction in a Uighur Population},
  author={Lei Wang and Yi-Tong Ma and Xiang Xie and Yining Yang and Zhen-Yan Fu and Xiao-Mei Li and Fen Liu and Ying Huang and Xiang Ma and Bang-dang Chen and Shan Yuan and Ming-Hui Sun and Xiao-Mei Peng and Bao-zhu Wang},
  journal={Clinical and Applied Thrombosis/Hemostasis},
  year={2012},
  volume={18},
  pages={72 - 78}
}
Objectives: Matrix metalloproteinase 9 (MMP-9) plays a pivotal role in early atherosclerosis, vascular remodeling, and development of arterial plaque rupture. The potentially functional MMP-9 gene polymorphism may contribute to the susceptibility of myocardial infarction (MI). We aimed to investigate the association between the interaction of 2 single-nucleotide polymorphisms ([SNPs] −1562C>T and R279Q) of the MMP-9 gene and smoking with MI in a Uighur population of China.Methods: A case… Expand
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