Interaction Analysis of Longevity Interventions Using Survival Curves

@article{Nowak2018InteractionAO,
  title={Interaction Analysis of Longevity Interventions Using Survival Curves},
  author={Stefan Nowak and Johannes Neidhart and Ivan G. Szendro and Jonas Rzezonka and Rahul Marathe and Joachim H A Krug},
  journal={Biology},
  year={2018},
  volume={7}
}
A long-standing problem in ageing research is to understand how different factors contributing to longevity should be expected to act in combination under the assumption that they are independent. Standard interaction analysis compares the extension of mean lifespan achieved by a combination of interventions to the prediction under an additive or multiplicative null model, but neither model is fundamentally justified. Moreover, the target of longevity interventions is not mean life span but the… 

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