Corpus ID: 42474459

Interacting genes that affect microtubule function in Drosophila melanogaster: two classes of mutation revert the failure to complement between haync2 and mutations in tubulin genes.

@article{Regan1990InteractingGT,
  title={Interacting genes that affect microtubule function in Drosophila melanogaster: two classes of mutation revert the failure to complement between haync2 and mutations in tubulin genes.},
  author={C. L. Regan and M. Fuller},
  journal={Genetics},
  year={1990},
  volume={125 1},
  pages={
          77-90
        }
}
  • C. L. Regan, M. Fuller
  • Published 1990
  • Biology, Medicine
  • Genetics
  • The recessive male sterile mutation haync2 of Drosophila melanogaster fails to complement certain beta 2-tubulin and alpha-tubulin mutations, suggesting that the haywire product plays a role in microtubule function, perhaps as a structural component of microtubules. The genetic interaction appears to require the presence of the aberrant product encoded by haync2, which may act as a structural poison. Based on this observation, we have isolated ten new mutations that revert the failure to… CONTINUE READING

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