Inter-subject Variability of LTD-like Plasticity in Human Motor Cortex: A Matter of Preceding Motor Activation

@article{Goldsworthy2014IntersubjectVO,
  title={Inter-subject Variability of LTD-like Plasticity in Human Motor Cortex: A Matter of Preceding Motor Activation},
  author={Mitchell R Goldsworthy and Florian M{\"u}ller-Dahlhaus and Michael C. Ridding and Ulf Ziemann},
  journal={Brain Stimulation},
  year={2014},
  volume={7},
  pages={864-870}
}
BACKGROUND Continuous theta burst stimulation (cTBS) of the human primary motor cortex (M1) induces long-term depression (LTD)-like plastic changes in corticospinal excitability, but several studies have reported high inter-subject variability of this effect. Most studies use a tonic voluntary contraction of the target muscle before cTBS to set stimulation intensity; however, it is unclear how this might affect response variability. OBJECTIVE To examine the influence of pre-activation of the… CONTINUE READING
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