Inter-cohort differences in coronary heart disease mortality in the 25-year follow-up of the seven countries study

  title={Inter-cohort differences in coronary heart disease mortality in the 25-year follow-up of the seven countries study},
  author={Alessandro Menotti and Ancel Benjamin Keys and Daan Kromhout and Henry W. Blackburn and Christ Aravanis and Bennie P. M. Bloemberg and Ratko Buzina and Anastasios S. Dontas and Flaminio Fidanza and Simona Giampaoli and MarttiJ. Karvonen and Mariapaola Lanti and Ivan Moha{\vc}ek and Sre{\'c}ko Nedeljkovi{\'c} and Aulikki Nissinen and Juha Pekkanen and Sven Punsar and Fulvia Seccareccia and Hironori Toshima},
  journal={European Journal of Epidemiology},
Sixteen cohorts of men aged 40–59 years at entry were examined with the measurement of some risk factors and then followed-up for mortality and causes of death for 25 years. These cohorts were located in the USA (1 cohort), Finland (2), the Netherlands (1), Italy (3), the former Yugoslavia (5), Greece (2), and Japan (2), and included a total of 12,763 subjects.Large differences in age-adjusted coronary heart disease (CHD) death rates were found, with extremes of 45 per 1000 in 25 years in… 
Forty-year coronary mortality trends and changes in major risk factors in the first 10 years of follow-up in the seven countries study
A strong positive association was found between the shape of the hazard curve, describing the acceleration of the risk, and a score of population mean risk factor changes observed during the first 10 years of follow-up, with a correlation coefficient of 0.91 between the two indicators.
Cardiovascular risk factors as determinants of 25-year all-cause mortality in the seven countries study
Individual multivariate analysis on eight national pools showed that age, systolic blood pressure, and smoking habits are direct, significant, and universal long-term predictors of all-cause mortality.
Comparison of multivariate predictive power of major risk factors for coronary heart diseases in different countries: results from eight nations of the Seven Countries Study, 25-year follow-up.
Great similarities were found in the multivariate coefficients of major coronary risk factors to CHD risk derived from population samples varying in CHD frequency.
Forty-Year Mortality From Cardiovascular Diseases and All Causes of Death in the US Railroad Cohort of the Seven Countries Study
Forty-year mortality and its association with entry risk factor levels is reported in men employed in the US Railroad industry within the Seven Countries Study of Cardiovascular Diseases.
Contribution of changes in risk factors to the decline of coronary heart disease mortality in Australia over three decades
  • Richard J. K. TaylorA. DobsonM. Mirzaei
  • Medicine
    European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology
  • 2006
Most of the spectacular decline in coronary heart disease mortality over the last three decades in Australia can be ascribed to reductions in population risk factors from primary and secondary prevention.
Risk factors for ischaemic heart disease in a Cretan rural population: a twelve year follow-up study
The study confirms the unfavorable risk factor profile of a well defined rural population in Crete and its actual effect on the observed incidence of coronary events in Cretans remains yet to be defined.
Ethnic inequalities in cardiovascular health
It is shown that immigrants from Former Yugoslavian countries have a higher total 10-year risk of CVD events than other ethnic groups and CVDs are preventable diseases, and this study adds new information about ethnic groups in Norway.
Incidence of Total Stroke, Stroke Subtypes, and Myocardial Infarction in the Japanese Population: The JMS Cohort Study
The incidence rate of stroke remains high, considerably higher than that of MI, in both men and women in Japan, and in the case of both sexes, the highest in the group of subjects aged > 70 years.


Seven Countries Study. First 20-year mortality data in 12 cohorts of six countries.
By applying the proportional hazards model to the pools of national cohorts, with CHD deaths as end-point and five risk factors as covariates, only age and mean blood pressure are universally significant predictors of fatal events.
The Yugoslavia cardiovascular disease study. II. Factors in the incidence of coronary heart disease.
In a 7-year follow-up of 11,121 Yugoslav men first examined in 1964-1965 when they were 35-62 years old, it was found that the incidence of coronary heart disease (CHD) was one-fourth that of a
Seven Countries: A Multivariate Analysis of Death and Coronary Heart Disease
During the last 30 years, epidemiologists have made remarkable progress in identifying important factors that are associated with the incidence of chronic diseases. Nowhere has this been more
Trends in cardiovascular disease mortality in industrialized countries since 1950.
  • K. UemuraZ. Píša
  • Medicine
    World health statistics quarterly. Rapport trimestriel de statistiques sanitaires mondiales
  • 1988
The considerable variation in mortality levels and trends observed among different countries points to the possibility for action by countries heavily affected by cardiovascular diseases and provides a basis for action and further research in each country and at the international level.
The diet and 15-year death rate in the seven countries study.
In 15 cohorts of the Seven Countries Study, comprising 11,579 men aged 40-59 years and "healthy" at entry, 2,288 died in 15 years, with all-cause and coronary heart disease death rates were low in cohorts with olive oil as the main fat.
Trends of mortality from ischaemic heart disease and other cardiovascular diseases in 27 countries, 1968-1977.
  • Z. PíšaK. Uemura
  • Medicine
    World health statistics quarterly. Rapport trimestriel de statistiques sanitaires mondiales
  • 1982
Ischemic heart disease mortality trends in the 27 developed countries for which reasonably reliable statistical data are available in the World Health Organizations data base are reviewed. An
Sources of the diet-heart controversy: confusion over population versus individual correlations.
The difference is illustrated between correlations of risk factors and disease found in individuals and those found between populations and an attempt is made to clarify the causal inference possible when these correlations are concordant and discordant.