Inter- and intramolecular enantioselective carbolithiation reactions

  title={Inter- and intramolecular enantioselective carbolithiation reactions},
  author={Asier G{\'o}mez-SanJuan and Nuria Sotomayor and Esther Lete},
  booktitle={Beilstein journal of organic chemistry},
In this review we summarize recent developments in inter- and intramolecular enantioselective carbolithiation reactions carried out in the presence of a chiral ligand for lithium, such as (-)-sparteine, to promote facial selection on a C=C bond. This is an attractive approach for the construction of new carbon-carbon bonds in an asymmetric fashion, with the possibility of introducing further functionalization on the molecule by trapping the reactive organolithium intermediates with… CONTINUE READING

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Showing 1-9 of 9 references

Carbolithiation of carbon-carbon multiple bonds

N. Sotomayor, E. Lete
In Science of Synthesis. Knowledge Updates • 2011
View 2 Excerpts

Intramolecular carbolithiation reactions of aryllithiums in the synthesis of carbocyclic and heterocyclic compounds

U. Martínez-Estíbalez, A. Gómez-SanJuan, +3 authors E. Lete
In Targets in Heterocyclic Systems; • 2010
View 2 Excerpts

Flash Chemistry. Fast Organic Synthesis in Microsystems

Yoshida, J.-i
View 1 Excerpt

Enantioselective carbolithiations. In Organolithiums in Enantioselective Synthesis

J. F. Normant
View 2 Excerpts

Regio - and stereoselective addition reactions of organolithiums

J. Clayden
Organolithiums : Selectivity for Synthesis • 2002

Regio- and stereoselective addition reactions of organolithiums. Organolithiums: Selectivity for Synthesis

J. Clayden
View 2 Excerpts

Generation and cyclization of unsaturated organolithiums

W. F. Bailey, T. V. Ovaska
Coxon, J. M., Ed.; Mechanisms of Importance in Synthesis, • 1994
View 1 Excerpt

Enantioselective carbolithiations

J. F. Normant
Organolithiums in Enantioselective Synthesis

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