Inter- and intralaboratory comparison of Ehrlichia equi and human granulocytic ehrlichiosis (HGE) agent strains for serodiagnosis of HGE by the immunofluorescent-antibody test.

@article{Walls1999InterAI,
  title={Inter- and intralaboratory comparison of Ehrlichia equi and human granulocytic ehrlichiosis (HGE) agent strains for serodiagnosis of HGE by the immunofluorescent-antibody test.},
  author={Jennifer J Walls and Maria Aguero-Rosenfeld and Johan S. Bakken and Jessica L. Goodman and Deloar Hossain and R. Colin Johnson and John Stephen Dumler},
  journal={Journal of clinical microbiology},
  year={1999},
  volume={37 9},
  pages={
          2968-73
        }
}
Human granulocytic ehrlichiosis (HGE) is usually diagnosed by immunofluorescent antibody (IFA) serology with Ehrlichia equi-infected neutrophils or HGE agent-infected cultured HL60 cells. The HGE agent and E. equi are antigenically diverse, and interpretation of serologic results is also often variable. Thus, we investigated the sensitivity and specificity of various HGE agent and E. equi antigens used for IFA diagnosis by three different laboratories. Serum samples from 28 patients with well… CONTINUE READING

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